Prof. Sarat Kumar Swain’s

Advanced Nanomaterials & Polymers Lab.

Veer Surendra Sai University of Technology, Burla

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Research

Drug Delivery

Drug delivery involves methods and technologies to transport drugs to specific body sites for optimal therapeutic effects. It aims to enhance drug efficacy, safety, and patient compliance by controlling how and where drugs are released. Delivery routes include oral, intravenous, topical, inhalation, and transdermal, each with unique benefits. Advanced systems like targeted delivery, controlled release, and nanotechnology improve drug effectiveness and reduce side effects, especially in treatments like cancer therapy.

Wound Healing

Wound healing is the body’s natural response to tissue injury, involving a coordinated process of stopping bleeding, managing inflammation, forming new tissue, and strengthening the repaired area. Key cells like platelets and fibroblasts help fight infection and rebuild skin. Healing can be quick in acute wounds or slow in chronic ones, influenced by factors such as health, age, and infection. Today’s treatments range from basic dressings to advanced options like growth factors and skin substitutes to enhance recovery.

Glucose Sensing

Glucose sensing is essential for effective diabetes management, involving a range of technologies that detect glucose levels in body fluids. Key methods include electrochemical sensors, which use enzymes to generate signals correlating with glucose concentration, and continuous glucose monitors (CGMs) that provide real-time tracking through subcutaneous sensors. Non-invasive techniques, such as those using infrared or ultrasound, offer potential for painless monitoring but still face accuracy challenges. Additionally, advanced implantable sensors and smart patches aim to deliver long-term, low-discomfort glucose monitoring. Ongoing advancements in sensor technology and data integration are making glucose monitoring more accurate, convenient, and tailored to individual needs.

Amino Acid Sensing

Amino acid sensing is the biological process through which cells detect and respond to the levels of amino acids, which are essential for protein synthesis, metabolism, and cell growth. This sensing is primarily mediated by pathways like mTOR (mechanistic target of rapamycin), which regulates cellular functions based on amino acid availability. Specialized sensors and transporters in cells monitor intracellular and extracellular amino acid concentrations, triggering responses that adjust nutrient uptake, protein synthesis, and energy balance. Amino acid sensing plays a crucial role in health and disease, influencing processes such as immune function, aging, and cancer progression.

Heavy Metal Sensing

Heavy metal sensing involves the detection and monitoring of toxic metals such as lead, mercury, cadmium, and arsenic in environmental, biological, or industrial samples. These metals can pose serious health and ecological risks even at low concentrations. Various sensing techniques, including electrochemical sensors, optical methods, and biosensors, are used for their rapid, sensitive, and selective detection. Advances in nanotechnology and molecular recognition elements, such as aptamers and metal-binding proteins, have improved the accuracy and portability of heavy metal sensors. Effective heavy metal sensing is crucial for environmental protection, public health, and regulatory compliance.

Energy Storage

Energy storage refers to the capture and retention of energy for later use, enabling a stable and reliable energy supply across various applications. It plays a critical role in balancing supply and demand, especially with intermittent renewable sources like solar and wind. Common energy storage technologies include batteries (such as lithium-ion), supercapacitors, flywheels, and thermal or mechanical storage systems. These systems store energy in chemical, electrical, or physical forms and release it when needed. Advances in materials science and engineering continue to improve the efficiency, capacity, and lifespan of energy storage solutions, supporting the transition to cleaner and more resilient energy systems.

Packaging

Packaging refers to the materials and methods used to protect, contain, and present products for distribution, storage, and consumption. It serves multiple functions, including safeguarding products from damage, contamination, and spoilage, while also providing information, branding, and marketing opportunities. Packaging can range from simple paper wraps to complex, multi-layered materials like plastics, metals, and glass, depending on the product’s needs. With growing environmental concerns, there is an increasing emphasis on sustainable packaging solutions, such as biodegradable materials and recyclable options, to reduce waste and minimize environmental impact.

Dye Removal

Dye removal refers to the process of eliminating synthetic dyes from wastewater, which are often used in industries like textiles, food, and cosmetics. These dyes can be harmful to the environment and human health if not properly treated. Common methods of dye removal include adsorption using materials like activated carbon, chemical oxidation, membrane filtration, and biological treatment. Advanced techniques, such as photocatalysis and electrochemical processes, are also being explored for their effectiveness in breaking down and removing dyes at lower concentrations. The goal is to reduce the environmental impact of dye-containing effluents and ensure clean water for ecosystems and human use.